fungi

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Posts posted by fungi

  1. 1 hour ago, Baccy said:

    They absolutley DID turn up positive. Then it was determined to be a false positive...?‍♂️

    Hey mate, thanks for originally posting about the failure of this vaccine trial, I'm not sure I would have heard about it otherwise. I definitely know what you're trying to convey here, but I think it warrants additional context because there is a difference between not expecting a positive HIV result (which later turns out to be a false) and knowing there's a possibility of false positives, but not expecting them to occur. In this case, it's the latter. From the NY Times:

     

    Quote

    The trouble that arose with the Australian vaccine, developed by the University of Queensland and the biotech company CSL, was related to its use of two fragments of a protein found in H.I.V.

    The protein formed part of a molecular “clamp” that researchers placed on the spikes that surround the coronavirus and allow it to enter healthy cells. The clamp stabilizes the spikes, allowing the immune system to respond more effectively to the vaccine.

    The use of the H.I.V. protein posed no risk of infecting the volunteers with that virus, the researchers said. But the clamp generated the production of antibodies recognized by H.I.V. tests at higher levels than the scientists had expected.

    Because H.I.V. tests could not be rapidly re-engineered to account for this, the researchers decided to abandon development of the vaccine. Proceeding could have led to widespread anxiety among Australians that the vaccine could cause AIDS.

    Science is fascinating!


     

    • Thanks 1
  2. 1 hour ago, Peekay said:

    Sure bud, its cleared for use and is being used in multiple countries for no reason at all, just a bit of a prank possibly?

    Italian doctors demanded its use for Covid because they were bored? along with Spain, Brazil, Mexico, France, US, Germany, Canada, UK and Japan....

    http://www.francesoir.fr/politique-monde/italy-council-state-says-yes-hydroxychloroquine-treatment-covid-19

    Thats enough now. I've not the slightest interest in its exact efficacy, that was never my point.

    Give it a few more weeks, as only time will answer these questions. Certainly not you or I.

    Have a great Xmas!

    Whether or not Hydroxycholoquine is used, or is cleared for use, wasn't the claim you originally made - its effective use was.  You've provided a source which makes extraordinary claims about the effective use of Hydroxycholoquine and I very clearly laid out why that source should be viewed with skepticism.

    If Hydroxycholoquine is an effective treatment for Covid-19, I would expect to see it outlined in an overwhelming number of treatment protocals for Covid-19 put forth by the health agencies associated with the countries you listed. I'm only familiar with the United States and you can find theirs here. Spoiler alert: Hydroxycholoquine is not included and they recommend against it here. Canada recommends against it too.

  3. 20 minutes ago, Peekay said:

    I can assure you that I am not cherry picking. Statements were made earlier in this thread by several people that Hydroxycholoquine was an entirely ineffective treatment for coronavirus.

    If anyone considers 164 seperate studies, carried out across 15 x countries and the subsequent data provided (which has been roundly ignored)  as nothing, well then there is not much else to say on the matter.

    I do appreciate your participation though, this should be an open discussion of facts not an attempted shutdown of discourse,. which it certainly has been.

    The reference to "164 studies and 15 countries" metric that keeps appearing in your posts seems to stem from information posted here: https://hcqmeta.com/ which as the site states is simply a "meta analysis of 164 studies". The authors, which aren't named, fail to include the criteria used to select the studies that appear in their analysis. Please take note of this claim:

    Quote

    Early treatment is most successful, with 100% of studies reporting a positive effect and an estimated reduction of 65% in the effect measured (death, hospitalization, etc.) using a random effects meta-analysis, RR 0.35 [0.27-0.46].

    How do you achieve 100% when there are numerous studies that do not conclude that Hydroxycholoquine is an effective treatment? It would seem they've purposely been omitted from this analysis. The authors of this article have narrowed their scope of studies for inclusion to those that only fit their narrative.

    Unnamed authors, a complete lack of methodology that could be used to understand how they analyzed each of the 164 studies, and no criteria for inclusion in the analysis - I'd hardly call this a credible source.

     

    • Like 2
  4. I'll take the vaccine as soon as it becomes available to me!

     

    8 hours ago, Peekay said:

    The Lancet report was pulled due to incorrect findings which just happened to suit the narrative at the time i.e. Hydroxychloroquine was dangerous whilst adding no benefit, they took it down for a very good reason, it was false. The clinical trials omit the drug Zinc & Z-pac combination, along with the early use of it.

     

    And again, it is used successfully throughout the world.

    http://www.francesoir.fr/politique-monde/italy-council-state-says-yes-hydroxychloroquine-treatment-covid-19

    Your claim is presented without evidence. The official reason given for retraction can be found here and seems to be widely accepted as accurate.

     

    Genuine question: is the link provided with your last statement offered as evidence to support the claim? If so, it fails to meet that bar:

    1. The focus of the article is Italy. A single country doesn't represent the world.

    2. The article mentions nothing about the effectiveness of Hydroxychloroquine, only that it can now be used for off-label treatment, which was previously prohibited. If we're defining success as: can Hydroxychloroquine be used as a treatment for Covid-19 in Italy? Then yes, but again, Italy is not the world and I think that falls outside the definition most people would associate with success in this situation: is Hydroxychloroquine an effective treatment for Covid-19.

    • Like 2
  5. I keep forgetting about this thread!

     

    I lit up one of my go to cheap and cheerfuls yesterday, a Quintero Panetela. Usually, I find these to be sweet with flavors of tobacco and baking spice, but this one was all cardboard and "thin". Sometime they're like that, but when they're on, they're really good.

     

    Lit up another and it was plugged. Tried to do some work with a toothpick, but it wasn't salvageable . My perfec draw arrives tomorrow!

    • Like 1

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